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KMID : 0882419960500040599
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Korean Journal of Medicine
1996 Volume.50 No. 4 p.599 ~ p.603
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A Case of Lithium Induced Nephrogenic Diabetes Insipidus Treated with Amiloride
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윤영무
김명곤/이 상/손장원/채형기/김상목/안유현/김호중
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Abstract
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In the treatment of affective disorders with lithium, nephrogenic diabetes insipidus is a common side effect. Lithium induces a vasopressin-resistant defect in urinary concentration of kidney. We described a 50 years old woman on chronic lithium
intake
for her manic-depressive disorder with polyuria due to nephrogenic diabetes insipidus and acute mental change with dehydration, but she was treated by hydration and amiloride effectively. This case reminded us that the amiloride could be used as
a
good
therapeutic agent for the lithium induced nephrogenic diabetes insipidus.
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KEYWORD
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